Randox Creatinine Reagent
CR 510. Rla. Picric Acid. 1x100ml
200 ml. Rlb. Sodium Hydroxide 1x100ml
CAL Standard 1x5.5ml
For the quantitative in vitro determination of Creatinine in serum, plasma or urine. This product is suitable for manual use and on the Rx monza analyser.
Creatinine is derived from creatinine and creatinine phosphate in muscle tissue and may be defined as a nitrogenous waste product. Creatinine is not reutilized but is excreted from the body in the urine via the kidney. It is produced and excreted at a constant rate which is proportional to the body muscle mass.
As a consequence of the way in which creatinine is excreted by the kidney, creatinine measurement is used mostly exclusively in the assessment of kidney function. Creatinine is regarded as the most useful endogenous marker in the diagnosis and treatment of kidney disease.
Creatinine is measured primarily to assess kidney function and has certain advantages over the measurements of urea. The plasma level of creatinine is relatively independent of protein ingestion, water intake,rate of urine production and exercise.
Since it rate of production is constant, elevation of plasma create is indicative of under-excretion, suggesting kidney impairment. Depressed levels of plasma creatinine are rate and not clinical significant.
Contents. Initial concentrations of solution
Rla. Picric Acid. 35 mmol/l
Rlb. Sodium Hydroxide 0.32 mol/l